WP9. Immuno-monitoring, immune profiling
| Sample/Species | Objective | Method/ Technique |
|---|---|---|
|
PBMC, Splenocytes |
Assessment of T cell responses |
ELISpot, ICS |
|
Serum |
Protein profiling |
Olink/Luminex |
|
PBMC, Splenocytes |
Transcriptomics |
scRNAseq |
|
PBMC, Splenocytes |
Gene expression analysis |
direct RNA hybridization (Nanostring) RNA-Seq bulk |
|
PBMC, Splenocytes Syrian Hamster, Mouse |
Assessment of T cell responses |
ELISpot, ICS |
|
Serum / Syrian Hamster, Mouse |
Assessment of B cell responses |
ELISA, MNT (VNT, PRNT 50) |