Pillar 2

WP 8. Pre-clinical non-animal models - In-vitro / OOC

System Type Objective

Lymphoid OOC

Non-animal

Compare immune responses to different influenza vaccination platforms

Human alveolar chip

Non-animal

Benchmark mouse & NHP equivalents

Human alveolar chip

Non-animal

Assess viral infection

ALI (Air-Liquid Interface)

Non-animal

Respiratory infections, host-parasite interactions and vaccine dellivery/efficacy

Human alveolar chip

Non-animal

Test LNP formulations